Cancer Institute Member Spotlight


July 19, 2019

Brendan Frett, Ph.D.

Brendan Frett, Ph.D.

Assistant Professor of Pharmaceutical Sciences UAMS College of Pharmacy Research Interest Statement Dr. Frett’s research focuses on small molecule drug design and developing enabling chemical methodologies to expedite the drug discovery process. In particular, he is interested in generating small molecules that have been strategically designed to modulate two or more targets in a given…


July 3, 2019

Igor Koturbash, M.D., Ph.D.

Igor Koturbash, M.D., Ph.D.

Associate Professor and Vice Chair Department of Environmental and Occupational Health Fay W. Boozman College of Public Health Co-Director Center for Dietary Supplements Research Research Interest Statement Being both M.D. and Ph.D., I have a long-lasting interest in diet and dietary supplements and their impact on human health. Therefore, the major focus of my research…


June 14, 2019

Kevin Raney, Ph.D.

Kevin Raney, Ph.D.

Professor and Chair Department of Biochemistry and Molecular Biology UAMS College of Medicine Research Interest Statement The Raney laboratory is interested in the mechanisms and functions of nucleic acid enzymes called helicases. Helicases play central roles in all aspects of DNA and RNA metabolism; therefore they are key enzymes in maintaining genomic stability. Genetic mutations…


June 11, 2019

Maurizio Zangari, M.D.

zangari

Professor Department of Hematology Oncology UAMS College of Medicine Director of Myeloma Bone Disease Research Research Interest Statement My research focuses on the clinical and preclinical aspects of bone disease. I first described the bone anabolic properties of proteasome inhibitors in myeloma patients and the effects on the PTH axis. Specifically, I investigated the effect…


May 23, 2019

Rangaswamy Govindarajan, M.D., M.R.C.P.(U.K.)

Rangaswamy Govindarajan, M.D., M.R.C.P.(U.K.)

Professor of Medicine Division of Hematology/Oncology Chief, Section of Hematology/Oncology, CAVHS Quality Officer, Cancer Service Line UAMS Winthrop P. Rockefeller Cancer Institute Clinical Research Interest Statement Dr. Govindarajan’s clinical interests are in the fields of gastrointestinal oncology and sarcoma. He treats patients with malignancy involving the entire GI tract, bone and soft tissue sarcomas. He…


May 14, 2019

Alan Tackett, Ph.D.

Professor of Biochemistry and Molecular Biology    UAMS College of Medicine Associate Director of Basic Research    UAMS Winthrop P. Rockefeller Cancer Institute Dr. Tackett’s research focuses on the identification of biomarkers and drug targets to treat melanoma. Specifically, he focuses on the identification of molecular and epigenetic pathways dysregulated in metastatic melanoma patients who…


April 25, 2019

Robert Eoff, Ph.D.

Robert Eoff, Ph.D.

Associate Professor Department of Biochemistry & Molecular Biology College of Medicine Biochemistry Track Leader for the Graduate Program in Interdisciplinary Biomedical Sciences Research Interest Statement DNA replication is a complex and perilous undertaking for the cell because the risk of incurring insults to the genome is greatest when the double-helix is unwound for copying. My research…


April 16, 2019

Justin W. Leung, Ph.D.

Justin W. Leung, Ph.D.

Assistant Professor Department of Radiation Oncology Biochemistry and Molecular Biology (secondary appointment) UAMS College of Medicine Research Interest Statement Tens of thousands of DNA damages occur per cell per day from endogenous metabolites, environmental and dietary carcinogens. It can threaten our genome integrity and promote tumor progression. To deal with this genotoxic challenge, our body…


March 27, 2019

Brian Koss

Brian Koss

Ph.D. Candidate UAMS College of Medicine Graduate Program in Interdisciplinary Biomedical Sciences Track: Biochemistry and Molecular Biology Mentor: Alan Tackett, Ph.D. Research Interest Statement Apoptosis in cancer and the immune system Development and regulation of the immune system Metabolic control of T cell fate and function My research focuses on identifying new approaches to combat…


March 14, 2019

Isabelle Racine Miousse, Ph.D.

Isabelle Racine Miousse, Ph.D

Assistant Professor Department of Biochemistry and Molecular Biology UAMS College of Medicine Research Interest Statement Cancer cells fundamentally differ from healthy cells in the way they metabolize the amino acid and methyl donor methionine. This phenomenon is known as methionine dependence. It manifests as an increased reliance on an exogenous supply of methionine for growth…



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