Myeloma Magazine | Fall 2016

  • From the Director

    Gareth Morgan, M.D., Ph.D

    Dear Readers, I am pleased to share with you my excitement about discoveries in myeloma biology that are unfolding at a rapid rate and raising the bar for effective, precision treatment. As you will learn in this issue of Myeloma, a collaborative international study has revealed gene variants that increase the risk of developing myeloma.…

  • From the Editor

    Janet Aronson

    The development of personalized medicine approaches to treating myeloma and related diseases takes center stage in this issue of Myeloma. With a wealth of patient sample-derived data, sophisticated systems for analyzing the data, and talented experts who can interpret the analyzed data, the Myeloma Center is making significant progress in the understanding of myeloma biology…

  • Big Data Analysis Fuels Personalized Medicine

    The bioinformatics team: (left to right) Chris Wardell, team leader, Michael Bauer, Amy Buros, Cody Ashby and Caleb Stein

    A truly unique feature of the Myeloma Center is its wealth of patient-derived clinical and research data. With more than 11,750 patients over a period of 27 years, the Myeloma Center has amassed a treasure trove of data elements, many at the molecular level, that have the potential to yield new understandings of disease biology and…

  • Twenty Years and Going Strong

    Left to right: Patricia Harrison-Yates and Sonja Thornes

    Patricia Harrison-Yates has been a myeloma survivor for a very long time. Twenty years, to be exact. She came to the Myeloma Center in 1996, underwent two transplants and has been doing well ever since. Originally from California, Harrison-Yates moved to Joplin, Missouri, when she and her then-husband were ready to start a family. During…

  • We Dig Crystals4Cancer!

    Bailey McNeill, 17 years old at the time, from Raleigh, North Carolina. McNeill had created a web-based business, Crystals4Cancer.com

    Last summer (2015) we shared with our readers a heartwarming story about Bailey McNeill, 17 years old at the time, from Raleigh, North Carolina. McNeill had created a web-based business, Crystals4Cancer.com, to sell her hand-crafted jewelry featuring crystals from the North Carolina mountains. Fueled by a desire to help cure myeloma, McNeill has been donating…

  • publication

    Clonal selection and double-hit events involving tumor suppressor genes underlie relapse in myeloma

    Clonal selection and double-hit events involving tumor suppressor genes underlie relapse in myeloma A new publication in Blood (2016 Sep 29;128(13):1735-44, PMID: 27516441) Primary Author: Niels Weinhold, M.D., Assistant Professor Despite the introduction of novel agents, relapse remains a challenge in the treatment of multiple myeloma. Understanding the underlying molecular mechanisms of myeloma growth and…

  • Our Budget for Research is more than 11.5 million

    YOUR SUPPORT ENABLES US TO TURN RESEARCH BREAKTHROUGHS INTO LIFESAVING TREATMENTS This year, we ask you to lend your support for our research in precision medicine and targeted treatment approaches. Our talented team of scientists and clinicians is deciphering the molecular genetics of each patient’s disease and developing novel strategies for personalized therapies. With an…

  • Not by Chance: Eight NEW Genetic Risk Factors Discovered for Multiple Myeloma

    Left to right: Dr. Gareth Morgan, Owen Stephens and Dr. Niels Weinhold

    National Human Genome Research Institute, National Institutes of Health Dr. Gareth Morgan, professor and director of the Myeloma Center, Dr. Niels Weinhold, assistant professor and director of genetics at the Myeloma Center, and colleagues from Germany, the Netherlands, Sweden, Iceland, and the United Kingdom have identified eight additional gene variants that increase the risk of…

  • An Active Outdoors Life Despite Myeloma

    In July 2007, Jim Dykstra did a lot of hard-core hiking. With his brother and nephew, he hiked to the bottom of the Grand Canyon and back up. It was a grueling three-day hike, and it was hot outside — 120 degrees. They also took long hikes in Bryce Canyon and Zion National Park. Dykstra…

  • “Now you all find a cure for this Disease”

    “Now you all find a cure for this Disease”

    This is the message that accompanied a donation from Owen and Cheryl Brown of Marietta, Georgia. Straight-forward and to-the-point.  Given, as was the donation, in the spirit of helping all patients and their families who are challenged by myeloma. When Cheryl Brown was diagnosed in 2015, she knew it was important to be treated by…

  • 'All in' for Clinical Care Excellence

    Holly Langster

    Caring, Compassionate, Skilled. These adjectives describe nurses that every patient wants at the bedside. They also apply to Holly Langster, the Myeloma Center’s director of clinical operations, who joined our team in July. An advanced practice nurse with more than 20 years of nursing experience, Langster holds a Doctor of Nursing Practice, a degree that…