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Winthrop P. Rockefeller Cancer Institute

Peter Emanuel

$1 Million Estate Gift to Benefit Breast Cancer Research at UAMS Cancer Institute

May 3, 2018 | LITTLE ROCK – A $1 million gift from the estate of Linda Garner Riggs to the Winthrop P. Rockefeller Cancer Institute at the University of Arkansas for Medical Sciences (UAMS) will be used to advance research of triple negative breast cancer. Riggs, who died in Nov. 2017, was a former Arkansas insurance commissioner and managing director at Stephens Inc.

“This gift will have long-lasting effects on UAMS’ ability to help women living with breast cancer. We are grateful to Mrs. Riggs for this transforming gift, which provides vital funds for our ongoing initiative for cancer research,” said UAMS Interim Chancellor Stephanie Gardner, Pharm.D., Ed.D.

A native of Fordyce, Riggs worked about 10 years in state government, serving as director of the research and committee staff of the Arkansas Legislature; legislative and budgetary director for Gov. Frank White; and insurance commissioner. She later joined Stephens Inc. where she worked for 25 years in corporate finance and as managing director of investment banking.

“Linda lived an exemplary life, and I was so privileged to know her and be her partner in it. She was a wonderful example and role model to anyone who wanted to become a better person,” said her husband, Lamar Riggs of Little Rock.

“We are honored and humbled that Mrs. Riggs designated the UAMS Cancer Institute as a recipient for this generous gift from her estate. Her foresight and dedication to the importance of cancer research will enable us to expand our efforts at understanding the causes of and improving the treatments for women with triple negative breast cancer and will move us closer to achieving National Cancer Institute (NCI) designation,” said Cancer Institute Director Peter Emanuel, M.D. Emanuel also serves as professor in the UAMS College of Medicine Division of Hematology.

NCI-designated cancer centers are recognized for their scientific leadership, resources, and research in basic, clinic and population science. There are 70 designated cancer centers in the United States, and the UAMS Winthrop P. Rockefeller Cancer Institute is in the process of pursuing this nationally recognized status.

In triple negative breast cancer, the cancer cells do not contain the hormones estrogen and progesterone or the protein HER2. Therefore, the most common hormonal therapies for breast cancer are not effective for women with this form of the disease, which is often aggressive and likely to spread or return after the initial diagnosis.

Triple negative breast cancer is diagnosed in up to 20 percent of cases and is more likely to occur in younger people, African-Americans, Hispanics and those with the BRCA1 gene mutation.

In appreciation of her gift, Riggs will be honored as a member of the 1879 Society of UAMS, recognizing all individuals who have made estate gifts to the university.

 

UAMS is the state's only health sciences university, with colleges of Medicine, Nursing, Pharmacy, Health Professions and Public Health; a graduate school; a hospital; a main campus in Little Rock; a Northwest Arkansas regional campus in Fayetteville; a statewide network of regional campuses; and seven institutes: the Winthrop P. Rockefeller Cancer Institute, Jackson T. Stephens Spine & Neurosciences Institute, Harvey & Bernice Jones Eye Institute, Psychiatric Research Institute, Donald W. Reynolds Institute on Aging, Translational Research Institute and Institute for Digital Health & Innovation. UAMS includes UAMS Health, a statewide health system that encompasses all of UAMS' clinical enterprise. UAMS is the only adult Level 1 trauma center in the state. UAMS has 3,240 students, 913 medical residents and fellows, and five dental residents. It is the state's largest public employer with more than 11,000 employees, including 1,200 physicians who provide care to patients at UAMS, its regional campuses, Arkansas Children's, the VA Medical Center and Baptist Health. Visit www.uams.edu or uamshealth.com. Find us on Facebook, Twitter, YouTube or Instagram.

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Five Grants Presented to UAMS Cancer Researchers

Jan. 29, 2018 | Five newly awarded grants will assist scientists at the UAMS Winthrop P. Rockefeller Cancer Institute in their search for new and innovative cancer treatments.

The grants of $10,000 each were presented to young investigators by the Envoys, a volunteer advocacy group of the Cancer Institute Foundation, during their “Doctor is In” reception and research poster showcase Jan. 25.

The grants are made possible by the Envoys’ annual RockStar Lounge fundraiser. This year’s event is set for April 13 at Cajun’s Wharf in Little Rock and will feature a performance by Bon Jovi tribute band Slippery When Wet.

“In an era when research funding has become more and more scarce, we are grateful to the Envoys for providing this essential support for our scientists,” said Cancer Institute Director Peter Emanuel, M.D. “With these start-up funds, they are able to establish the preliminary data needed to secure additional larger grants in the future.”

Recipients of the grants were:

Burdine’s project focuses on a novel approach to regulating a protein known as ATAD2 that is highly expressed in several types of cancer, including breast, pancreas, colon and liver, as well as in metastatic disease. If successful, regulation of the protein could lead to new therapies for these types of cancer.

  • Brendan Frett, Ph.D., assistant professor in the Department of Pharmaceutical Sciences, UAMS College of Pharmacy

Precision lung cancer treatment is often effective only for the short term due to significant differences that appear in individual cases of the disease. Frett’s objective is to improve the long-term outcomes of precision lung cancer therapy by simultaneously targeting multiple facets of the disease. He will synthetically engineer single molecule drug candidates capable of impairing multiple tumor survival pathways.

  • Samantha Kendrick, Ph.D., assistant professor in the Department of Biochemistry and Molecular Biology, UAMS College of Medicine

Kendrick’s project focuses on understanding how and why certain genes repeatedly mutate and contribute to the aggressive nature of B-cell lymphoma. Her research examines the frequency of DNA structures in these specific gene targets and whether the structures contribute to an increased susceptibility to mutation. Uncovering this process can facilitate the design of new therapies to minimize the risk of chemotherapy resistant disease.

Although advances in immunotherapy have offered great promise for several types of cancer, outcomes for an aggressive form of brain cancer known as glioblastoma remain grim. Rodriguez’s project uses the surgical technique laser thermal ablation in combination with immunotherapy to alter the immune microenvironment, cause cancer cell death and open the area around the tumor in an effort to improve outcomes for patients with this disease.

Tian’s research addresses the role of two alias proteins produced by the gene MYC in the outcome of patients with multiple myeloma. He seeks to understand how one of these proteins affects the other in regard to cell proliferation and will use this knowledge to deliberately induce a different translation and modification of the gene that could ultimately lead to preventing uncontrollable cancer growth.

UAMS Breast Surgeon Ronda Henry-Tillman, M.D., Named to Kohn Chair in Breast Surgical Oncology

Nov. 30, 2017 – Ronda Henry-Tillman, M.D., F.A.C.S., was invested Nov. 29 as recipient of the Muriel Balsam Kohn Chair in Breast Surgical Oncology at the University of Arkansas for Medical Sciences (UAMS). She is chief of Breast Oncology in the UAMS College of Medicine Department of Surgery.

The endowed chair is the result of a gift from the Tenenbaum Foundation. The foundation’s primary objectives include providing humanitarian assistance to residents of central Arkansas, promoting awareness of breast cancer, and funding research to reduce or eliminate deaths from the disease.

The chair is named in honor of Muriel Balsam Kohn, mother of Judy Tenenbaum, who died of breast cancer in 1993.

“I am thankful for the generosity and foresight of the Tenenbaum Foundation in establishing this endowed chair, which has enabled valuable breast cancer research to be conducted in Arkansas for the past 10 years. This legacy will continue for many years to come through the work and dedication of Dr. Henry-Tillman,” said UAMS Interim Chancellor Stephanie Gardner, Pharm.D., Ed.D., who also serves as senior vice chancellor for academic affairs and provost.

An endowed chair is among the highest academic honors a university can bestow on a faculty member and is established with gifts of $1 million, which are invested and the proceeds used to support the educational, research and clinical activities of the chair holder. Those named to a chair are among the most highly regarded scientists, physicians and professors in their fields of expertise.

“Dr. Henry-Tillman has been a valuable member of the UAMS faculty since 1998, not only serving as a knowledgeable and caring physician for countless women, but also as a tireless advocate for underserved Arkansans who lack basic health care services. There is no doubt that her work to improve access to mammography services has extended the lives of women across our state,” said UAMS Cancer Institute Director Peter Emanuel, M.D., who also serves as professor of medicine in the UAMS College of Medicine.

NBA Hall of Famer and philanthropist Dikembe Mutombo addressed the attendees gathered to honor Henry-Tillman at a Nov. 29 ceremony, praising her work at educating health providers in Africa, including at the Biamba Marie Mutombo Hospital he founded 10 years ago in the Democratic Republic of the Congo.

Henry-Tillman’s mentor, Groesbeck P. Parham, M.D., recruited her to travel to Africa where she has taught breast surgical techniques and medical procedures to health care providers who have limited access to equipment and advanced educational opportunities. Parham is a professor of obstetrics and gynecology at the University of North Carolina, Chapel Hill.

After earning her medical degree at the University of California San Diego School of Medicine, Henry-Tillman completed her surgical residency in the UAMS Department of Surgery and fellowship training in the UAMS Fellowship in Diseases of the Breast program.

She holds the positions of professor in the Department of Surgery, co-director of Health Initiatives and Disparities Research in the UAMS College of Medicine, and co-leader of the Breast Tumor Disease Oriented Committee in the UAMS Winthrop P. Rockefeller Cancer Institute.

She previously served as director of the UAMS Cancer Control program and was instrumental in the development of the university’s mobile mammography program.

Her research efforts have focused primarily on health initiatives that address access, community-based participatory research, health disparities and health policy in the areas of breast, prostate, colorectal, and cervical cancer prevention.

In 2016, Henry-Tillman was appointed by Gov. Asa Hutchinson to the Arkansas Medical Marijuana Commission and was voted chairman in 2017. She also is a member of the Breast Cancer Control Advisory Board and is a Pulaski County health officer for the Arkansas State Board of Health.

Her memberships and professional activities include the American Surgical Association, Society of Surgical Oncology, Southern Surgical Association, Society of Black Academic Surgeons, National Medical Association, American Society of Breast Surgeons and multiple committees of the National Institutes of Health. She has served as a board member for the National Accreditation Program for Breast Centers and the national Health Disparities Committee for the American Cancer Society, as well as the Arkansas Cancer Coalition and other local organizations.

She has received numerous awards and honors including being named to the Alpha Omega Alpha Honorary Medical Society, Best Doctors in America and Castle Connolly’s Exceptional Women in Medicine. She is recipient of the Shipley Award by the Southern Surgical Association; the Rosetta Wilkins Award by BreastCare; the President’s Award by the Arkansas Medical and Dental Pharmaceutical Association; the President’s Award by the Arkansas Democratic Black Caucus. She also has received the Phenomenal Woman in Science and Excellence in STEM Mentoring awards.

The Tenenbaum Foundation was created in 1964 by Joe M. Tenenbaum. The foundation created the chair’s endowment in 2007 to recognize Kohn and the chair’s first holder V. Suzanne Klimberg, M.D., Ph.D., former director of the UAMS Division of Breast and Surgical Oncology. Klimberg now serves as medical director of the University of Texas Medical Branch Cancer Center in Galveston, Texas.

Speakers at the Nov. 29 ceremony included Gardner, Emanuel, Klimberg, Parham, Mutombo and the following:

  • Pope L. Moseley, M.D., UAMS executive vice chancellor and dean of the UAMS College of Medicine
  • Kent C. Westbrook, M.D., distinguished professor of surgery in the UAMS College of Medicine
  • Frederick R. Bentley, M.D., professor and chairman of the Department of Surgery in the UAMS College of Medicine

$7,000 Donation to UAMS Cancer Institute Honors Memory of Stuttgart Woman

LITTLE ROCK –A donation of $7,000 in memory of the late Stacey Gabriel Homra of Stuttgart will benefit cancer research conducted by the Winthrop P. Rockefeller Cancer Institute at the University of Arkansas for Medical Sciences (UAMS).

The donation was presented Nov. 14 to Cancer Institute Director Peter Emanuel, M.D., by Homra’s husband, Allen Homra, and long-time friend, Melanie Baden. Baden raised the money through an online fundraising campaign following Homra’s death in September from glioblastoma, a rare form of brain cancer.

The campaign was conducted in conjunction with Baden’s hike through a section of the Appalachian Trail known as the 100-mile wilderness. Having already hiked 1,250 miles of the trail, which extends from Springer Mountain in Georgia to Mount Katahdin in Maine, Baden will complete the total 2,189-mile trek in May 2018.

“I started the 100-mile wilderness hike on Oct. 5. Because Stacey passed away a few days before that, I decided to use that hike as a way to honor both her memory and the dedication of her husband, Allen, and daughter, Madison,” Baden said.

Her campaign raised $7,000 in 13 days, with many donations coming from as far away as California and Hawaii, in addition to many from Stuttgart friends and relatives. It will be used to support cancer research at UAMS, where Homra underwent treatment following her diagnosis in 2014.

“We are grateful to Ms. Baden for her foresight in raising these funds and to Mr. Homra for choosing to designate them for cancer research. The generosity of each person who donated to this campaign will have an impact in our ongoing fight against cancer,” said Emanuel, who also serves as a professor in the UAMS College of Medicine.

Baden will accept additional donations in honor of the Homras when she resumes her hike in the coming months.

Annual Gala for Life Raises $942,000 for UAMS Winthrop P. Rockefeller Cancer Institute

Oct. 11, 2017 | The bright lights of New York City shone on Little Rock on Sept. 15 when the UAMS Winthrop P. Rockefeller Cancer Institute hosted its 22nd annual Gala for Life.

The black-tie event, held at Little Rock’s Statehouse Convention Center, brought together 740 supporters from throughout Arkansas and raised about $942,000 for the fight against cancer. A portion of the net proceeds will directly benefit the UAMS Cancer Genetics Program, which includes Arkansas’ only board-certified geneticists who diagnose, manage and treat complex cancer syndromes.

Arkansas native and three-time Tony Award-winning Broadway producer Remmel T. Dickinson served as event chair. KTHV news anchor Craig O’Neill was master of ceremonies.

“We are so thankful for the leadership of Remmel Dickinson and for our generous sponsors who make this event possible. All of the money raised by the Gala of Life stays in Arkansas and is used to help us advance our ability to prevent, diagnose and treat cancer,” said Peter Emanuel, M.D., Cancer Institute director and professor in the UAMS College of Medicine.

Gala for Life presenting sponsors were the Willard and Pat Walker Charitable Foundation Inc. and Highlands Oncology Group.

Donations made by guests that evening were matched by Nan Ellen and Jack M. East; Peggy and Haskell Dickinson; and Mary Kay and Dr. F.E. Joyce and family. View a complete list of sponsors here.

Dinner entertainment included performances by Michael Buble tribute artist Scott Keo; a musical revue by Broadway performers Dan’yelle Williamson and Kevin Massey; and a special performance by “America’s Got Talent” finalist and sand story artist Joe Castillo.

Guests also enjoyed a cocktail reception featuring the sights and sounds of New York City’s Rockefeller Center and Times Square, complete with ice skaters, food carts, street performers, digital caricature artists and a virtual graffiti wall.

Robin Dean Honored by UAMS Cancer Institute Auxiliary

May 3, 2017 | Gracious, calm and compassionate were just three of the words used to describe Robin Dean at an April 26 ceremony honoring her service to the UAMS Winthrop P. Rockefeller Cancer Institute.

“Robin looks for the sun when the clouds hit. She brings a positive attitude to everything she does,” said Kent Westbrook, M.D., addressing a crowd of more than 160 people gathered to honor Dean as the UAMS Cancer Institute Auxiliary’s 2017 Distinguished Honoree. The award is presented each year to a person who has made an outstanding contribution to the mission of the Cancer Institute.

Westbrook is a distinguished professor in the UAMS College of Medicine and co-founder of the Cancer Institute.

“While we have had many physicians and scientists receive this honor over the past 23 years, Robin is only the second staff member to be named our Distinguished Honoree. The Cancer Institute is truly a better place thanks to Robin’s grace and compassion,” said Peter Emanuel, M.D., Cancer Institute director and professor of medicine in in the UAMS College of Medicine.

A three-time cancer survivor, Dean devoted more than two decades as both a volunteer and staff member at the Cancer Institute. Her volunteer activities included serving as chair of auxiliary fundraising events and as an auxiliary board member, including a stint as president in 1999-2000. She was named Volunteer of the Year in 2001.

Her staff positions included serving for two years as a salesperson in the Cancer Institute Gift Shop and for 13 years as coordinator for the Cancer Institute Cancer Support Center at the Family Home, a nonprofit facility that provides low-cost housing for cancer patients and parents of infants in the UAMS Neonatal Intensive Care Unit. She retired in 2016.

“You have diagnosed me and treated me. You’ve prayed for me and cared for me. There is no doubt that God’s hand has guided me during these years,” said Dean, acknowledging the health care team and friends who cared for her during her cancer treatments. “Who would have thought that having cancer would have prepared me to talk to the patients I met at the Family Home about how to keep hope alive?”

The Cancer Institute Auxiliary is one of Arkansas’ largest volunteer organizations with more than 500 members dedicated to providing information, service, compassion and hope to those whose lives are touched by cancer.

Janie Lowe serves as director of the UAMS Cancer Institute Department of Volunteer Services and Auxiliary.

Radiation Effects Expert Martin Hauer-Jensen Invested in J. Thomas May Distinguished Endowed Chair in Oncology

Sept. 1, 2016 | The family of the late William E. “Bill” Clark has given $300,000 to establish a distinguished endowed chair in honor of J. Thomas May in which world-renowned radiation effects expert Martin Hauer-Jensen, M.D., Ph.D., was invested Aug. 29 at the University of Arkansas for Medical Sciences (UAMS).

Hauer-Jensen, a professor of pharmaceutical sciences, surgery and pathology, is director of the Division of Radiation Health in the UAMS College of Pharmacy.

A distinguished endowed chair is the highest academic honor a university can bestow on its faculty and is established with gifts of $1.5 million or more to support the educational, research and clinical activities of the chairholder. Those named to a chair are among the most highly regarded scientists, physicians and professors in their fields of expertise.

The J. Thomas May Distinguished Endowed Chair in Oncology was funded by the family of Clark, who was chairman and CEO of CDI Contractors in Little Rock, to honor his friend May, former CEO of Simmons First National Corp.

“The Clarks’ generous gift ensures that UAMS can continue providing the highest quality oncology physicians and researchers in Arkansas. Bill Clark and Tommy May share a legacy of dedicated service,” said UAMS Chancellor Dan Rahn, M.D. “Their friendship is a wonderful testimony to the importance of relationships and the power of two friends sharing a common goal to improve the future of health care for others.”

An endowed chair was established in 2006 with $1 million from Bill and Margaret Clark. Bill Clark died of cancer one year later. The initial investment grew by $200,000 over the last decade. In June, Margaret Clark, and her son, William E. Clark II, chairman of the UAMS Foundation Fund Board, gave another $300,000 to elevate the chair to a distinguished endowed chair. It is the first distinguished endowed chair for a faculty member of the UAMS College of Pharmacy.

“We thank the Clark family from the bottom of our hearts for this additional gift. This will benefit our oncology program from now on into the future,” said Peter Emanuel, M.D., executive director of the UAMS Winthrop P. Rockefeller Cancer Institute.

Bill Clark, a former member of the UAMS Foundation Fund Board, became friends with May when the two served together for nine years on the University of Arkansas Board of Trustees. “It was a friendship like I’d never seen before,” Margaret Clark has said.

A resident of Pine Bluff, May has an extensive background in civic and community service, for which he has received numerous awards, and served on the UAMS Department of Psychiatry capital campaign steering committee. He holds an honorary doctorate of law from the University of Arkansas at Pine Bluff.

In addition to Rahn, Emanuel and William E. Clark II, speakers at the ceremony included Stephanie Gardner, Pharm.D., Ed.D., UAMS provost and chief academic officer; Keith M. Olsen, Pharm.D., dean of the College of Pharmacy; and James W. Hardin, Ph.D., chief scientific and administrative officer for SunEcoEnergy Inc., who formerly worked with Hauer-Jensen at the UAMS Cancer Institute. University of Arkansas System President Donald Bobbitt, Ph.D., was also in attendance.

Hauer-Jensen was presented with a commemorative medallion by Rahn and Olsen.

“I thank the Clark family and Tommy May for making this distinguished endowed chair possible, and Peter Emanuel for organizing it. I am looking forward to working with Dean Olsen to enhance the competitiveness of the Division of Radiation Health,” Hauer-Jensen said.

“None of this would be possible without my family,” he continued. “I’ve had many long nights, many business trips, and many weekends that I could not be with them, and I give them my sincere, heartfelt thanks.”

Gardner, who was dean of the College of Pharmacy when Hauer-Jensen was recruited, praised his leadership and his work mentoring a new generation of researchers. “I have been looking forward to this day for almost a decade,” Gardner said. “Martin’s strong leadership and vision are what draw people to this division. He’s not just an internationally recognized scientist; he’s a visionary, a mentor, a leader, and a coach.”

Hauer-Jensen is an internationally recognized authority on normal tissue radiation responses. His research focuses on determining mechanisms of injury and developing strategies to prevent adverse effects after radiation therapy in cancer patients, to make radiation therapy for cancer safer and more effective.

He joined the UAMS faculty in 1990 to launch a career in academic surgery. In 2008, Hauer-Jensen moved from the College of Medicine to the College of Pharmacy and was appointed associate dean for research and director of the newly formed Division of Radiation Health in the Department of Pharmaceutical Sciences.

Hauer-Jensen is president of the Radiation Research Society and serves on numerous national and international advisory boards, review panels and editorial boards.

At UAMS, he co-leads the Host Response and Radiation Sciences program at the Winthrop P. Rockefeller Cancer Institute. He has been chair of the Radiation Study Section of the National Institutes of Health, a consultant on radiological emergencies to the World Health Organization, and a member of the National Council on Radiation Protection and Measurements.

He has published more than 250 scientific papers and has received peer reviewed research funding for more than 20 years. He is the recipient of the coveted MERIT Award from the National Cancer Institute.