NCT04920474 – Protocol for a Research Sample Repository for Allogeneic Unrelated Hematopoietic Stem Cell Transplantation

The primary purpose of the Research Sample Repository is to make blood samples available for research studies related to histocompatibility and hematopoietic cell transplantation (HCT) or other cellular therapy.

Representatives of participating centers and investigators or research groups may request access to research samples contained in the Research Sample Repository for the purpose of conducting research including:

• investigating molecular explanations for histocompatibility or clinical outcomes through analysis of genomic, epigenetic, or other biomolecular data
• evaluating the factors that affect transplant or cellular therapy outcome
• studying the distribution of HLA tissue types in different populations
• studying the success of transplantation, cellular therapies or supportive care in the management of marrow toxic injuries
• performing de-linked (anonymous) research