Meeting Time
The Cancer Biology Program meets every month on the 4th Tuesday at 4:00pm. Please contact Laura Rakes for more information at alrakes@uams.edu.
Mission Statement
The mission of the CBP is to provide basic discoveries and promote research collaborations that lead to new approaches for preventing and treating cancer.
Specific Aims: The overarching goal of the CBP is to improve understanding of the biochemical, molecular, and cellular mechanisms underlying tumor development, progression, and metastasis. To achieve this goal, research in the CBP has the following aims:
- Aim 1: Delineate mechanisms by which cells maintain genomic integrity and how these mechanisms are involved in the development and progression of cancer.
- Aim 2: Define the contribution of stromal elements in determining tumor behavior and patient response to therapy.
- Aim 3: Understand the immune response to cancer and the mechanisms that suppress this response in tumors.
Primary Areas of Research
Viral Oncology
Viral Oncology includes both how viruses initiate tumor formation and how viruses can be used to target tumor cells.
Tumor Immune Response
Tumor immune response looks at how T cells change their behavior in a tumor and how those changes can be reverted back to the normal immune response.
Vaccine Targets
Vaccine targets examine new targets for vaccines and how to make them more effective.
From Bench to Bedside
Discoveries made by Cancer Biology program investigators are used together with those from the other Cancer Institute research programs to advance translational and clinical research.
Program Leader Steven Post
“Cancer biology is very broad based as it applies to basic science discovery. However, our program focuses on understanding the basic science as it relates to tumor cell development and how a cell’s environment either supports or inhibits tumor growth.”
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