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  1. University of Arkansas for Medical Sciences
  2. Winthrop P. Rockefeller Cancer Institute
  3. Research
  4. Shared Resources
  5. Proteomics

Proteomics

The IDeA National Resource for Quantitative Proteomics provides a full range of services for protein characterization by mass spectrometry, including protein identification, mapping of post-translational modifications, global proteomics, and quantitative comparison of proteins in biological samples using state-of-the-art equipment.

Contact

Please contact us at IDeAproteomics@uams.edu to discuss how we can support your research.

Robot microfluidics dispensation

Overview

Our services are comprehensive, including:

  1. Complete sample preparation starting from cultured cells;
  2. Frozen or FFPE tissue samples;
  3. Serum or plasma samples;
  4. Immunoprecipitation (IP); and
  5. Other affinity purifications and biological samples.

Comprehensive data analysis is also included with all services.

Services

Discovery Proteomics Services

  • Cell/Tissue Protein Extraction and Protease Digestion
  • Plasma/Serum Protein Depletion
  • Histone Extraction
  • SDS-PAGE and In-Gel Trypsin Digestion
  • Isobaric Labeling
  • Phosphopeptide Enrichment
  • Peptide Fractionation
  • Data-Independent Analysis

Targeted Proteomics Services

  • SRM and PRM Analysis
  • HRAM Analysis
  • Targeted Assay Development

Bioinformatics Services

  • Full Data Analysis Support for Discovery and Targeted Services
  • Mascot and MaxQuant Database Searches
  • proteiNorm
  • ProteoViz
  • PTMViz
  • Targeted Analysis

Computing Resources

  • High Performance Computing (HPC) Cluster
  • PowerStation GX2
  • Dell Windows PCs

Equipment

  • Orbitrap Tribrid Mass Spectrometers
  • Orbitrap Exploris 480 Mass Spectrometer
  • Bruker timsTOF Pro 2 Mass Spectrometer
  • TSQ Quantiva Mass Spectrometer
  • Q Exactive Plus Mass Spectrometer
  • UltiMate 3000 Binary Analytical Liquid Chromatography System
Winthrop P. Rockefeller Cancer Institute LogoWinthrop P. Rockefeller Cancer InstituteWinthrop P. Rockefeller Cancer Institute
Address: 449 Jack Stephens Dr., Little Rock, AR 72205
Parking Deck: 4018 W Capitol Ave, Little Rock, AR 72205
Appointments: (501) 296-1200
Referring Physicians: (501) 686-6080
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